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Vertical infusion (self-emptying) bags used for Intravenous infusion are typically obtained by moulding a soft envelope of polypropylene. In normal conditions a continuous flow of liquid can be obtained with no need to use a pump. In the present study, the relationship between air pressure effects and the drug drip rate have been investigated experimentally and numerically. After determining relevant experimental data about the descending height of liquid level, the dropping speed and pressure, the ordinary least square method and MATLAB have been used to reconstruct the related variation and interrelation laws. Numerical simulations have been performed to determine the best gas-liquid volume ratio and improve the overall performances of these bags. According to these results, that the biggest effect on the drip rate is produced by the diameters of the used needles.

Experimental and Numerical Analysis of the Relationship between Pressure and Drip Rate in a Vertical Polypropylene Infusion Bag