Open AccessAN INTERVENTIONAL STUDY OF LOW DOSE HUMAN MENOPAUSAL GONADOTROPIN WITH CLOMIPHENE CITRATE FOR OVULATION INDUCTION IN CLOMIPHENE RESISTANT POLYCYSTIC OVARIAN SYNDROME WOMEN IN THE DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY, SMS MEDICAL COLLEGE, JAIPUR
Author(s) -
Deepshikha Gupta,
Narendra Joshi,
Suman Lata Mendiratta
Publication year - 2021
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v5i8.2098
Subject(s) - ovulation induction , medicine , infertility , gynecology , ovulation , obstetrics and gynaecology , polycystic ovary , obstetrics , ovarian hyperstimulation syndrome , clomifene , letrozole , pregnancy , in vitro fertilisation , insulin resistance , insulin , hormone , biology , cancer , breast cancer , tamoxifen , genetics
Background:
Methods: The present study is a single arm interventional study done at a tertiary care hospital in a metropolitan city. The study participants were the females who had infertility due to PCOS and resistant to clomiphene citrate, and participants were given HMG in a sequential manner with Clomiphene citrate and ovulation was observed using the TVS.
Results: 79% of the study participants ovulated at the end of the study as a final outcome and only 25 participants who constitute 21% of the total had not ovulated. No cases of ovarian hyperstimulation and multiple gestation was reported.
Conclusion: The study thus concludes that CC with low dose HMG is an efficient and safe method for induction of ovulation in females with CC resistant PCOS related infertility without the dangers of OHSS and other adverse events, also the presence of normal BMI can help in a better rate of ovulation
Keywords: HMG, TVS, Infertility