Open AccessEstablishing Equivalent Aerobic Exercise Parameters Between Early-Stage Parkinson’s Disease and Pink1 Knockout Rats
Author(s) -
Michael F. Salvatore,
Isabel Soto,
Ella A. Kasanga,
Rachael James,
Marla K. Shifflet,
Kirby Doshier,
Joel T. Little,
Joshia John,
Helene Alphonso,
J. Thomas Cunningham,
Vicki A. Nejtek
Publication year - 2022
Publication title -
journal of parkinson's disease/journal of parkinson's disease (online)
Language(s) - English
Resource type - Journals
eISSN - 1877-718X
pISSN - 1877-7171
DOI - 10.3233/jpd-223157
Subject(s) - aerobic exercise , treadmill , heart rate , medicine , regimen , parkinson's disease , exercise intensity , physical medicine and rehabilitation , physical therapy , disease , cardiology , psychology , blood pressure
Rodent Parkinson's disease (PD) models are valuable to interrogate neurobiological mechanisms of exercise that mitigate motor impairment. Translating these mechanisms to human PD must account for physical capabilities of the patient.