Open AccessPrecision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project
Author(s) -
Kat Toups,
Ann Hathaway,
Deborah R. Gordon,
Henrianna Chung,
Cyrus A. Raji,
Alan Boyd,
Benjamin D. Hill,
Sharon Hausman-Cohen,
Mouna Attarha,
Won Jong Chwa,
Michael Jarrett,
Dale E. Bredesen
Publication year - 2022
Publication title -
journal of alzheimer's disease
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-215707
Subject(s) - medicine , cognitive decline , dementia , randomized controlled trial , montreal cognitive assessment , adverse effect , memantine , clinical trial , neurocognitive , disease , cognition , psychiatry
Effective therapeutics for Alzheimer's disease are needed. However, previous clinical trials have pre-determined a single treatment modality, such as a drug candidate or therapeutic procedure, which may be unrelated to the primary drivers of the neurodegenerative process. Therefore, increasing data set size to include the potential contributors to cognitive decline for each patient, and addressing the identified potential contributors, may represent a more effective strategy.