Open AccessBetahydroxybutyrate Consumption in Autopsy Brain Tissue from Alzheimer’s Disease Subjects
Author(s) -
Russell H. Swerdlow,
Mony J. de Leon,
David L. Marcus
Publication year - 2021
Publication title -
journal of alzheimer's disease reports
Language(s) - English
Resource type - Journals
ISSN - 2542-4823
DOI - 10.3233/adr-210002
Subject(s) - ketone bodies , autopsy , bioenergetics , alzheimer's disease , brain aging , medicine , disease , endocrinology , pathology , mitochondrion , biology , metabolism , biochemistry
Alzheimer's disease (AD) features perturbed brain glucose utilization, which could contribute to brain bioenergetic failure. This led some to consider using ketone bodies to enhance AD brain bioenergetics and treat AD.