Open AccessAPOE ɛ4 Allele and Financial Capacity Performance in Mild Alzheimer’s Disease: A Pilot Study
Author(s) -
Vaitsa Giannouli,
Magda Tsolaki
Publication year - 2021
Publication title -
journal of alzheimer's disease reports
Language(s) - English
Resource type - Journals
ISSN - 2542-4823
DOI - 10.3233/adr-200254
Subject(s) - apolipoprotein e , allele , neuropsychology , disease , neuropsychological test , alzheimer's disease , medicine , cardiology , psychology , cognition , psychiatry , genetics , biology , gene
This study aims to explore a little investigated topic, i.e., whether the presence of the APOE eɛ4 allele in patients with a diagnosis of mild Alzheimer’s disease (AD) can influence financial capacity. Twenty-eight elders with mild AD carrying the APOE ɛ4 allele and 28 matched non-carrier patients were examined with an extensive battery of neuropsychological tests, and a specific test measuring financial capacity: Legal Capacity for Property Law Transactions Assessment Scale (LCPLTAS). The presence of the APOE ɛ4 allele does not differentiate the group of mild AD patients regarding a number of cognitive domains necessary for financial capacity scores as measured by LCPLTAS.