Open AccessBiomarker characterization in endometrial cancer in Italy: first survey data analysis
Author(s) -
Gian Franco Zani,
Angela Santoro,
Nicoletta D’Alessandris,
Giulia Scaglione,
Frediano Inzani,
Giuseppe Angelico,
Emma Bragantini,
Alessia Piermattei,
Federica Cianfrini,
Brigitte Bisarò,
Matteo Fassan
Publication year - 2022
Publication title -
pathologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.243
H-Index - 18
eISSN - 1591-951X
pISSN - 0031-2983
DOI - 10.32074/1591-951x-775
Subject(s) - pms2 , msh2 , microsatellite instability , msh6 , endometrial cancer , mlh1 , lynch syndrome , medicine , oncology , gynecology , cancer , biology , colorectal cancer , dna mismatch repair , genetics , microsatellite , allele , gene
Endometrial carcinoma (EC) is the most common gynecological malignant disease in high income countries. The 2020 edition of the World Health Organization (WHO) Classification of Tumors of the Female Genital Tract underlines the important clinical implications of the new integrated histo-molecular classification system, in order to correctly define the specific prognostic risk group. This survey analysis will focus on the most commonly adopted immunohistochemical and molecular biomarkers used in daily clinical characterization of a diagnosed endometrial carcinoma in Italian labs.