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There are many publications that deal with administration of test substances to animals and removal of blood samples for different objectives. Parenteral route of drug administration includes further different routes i.e., drug administration through muscles (IM route) through veins (IV route) and through subcutaneous route. We can manage to check the outcomes of test substances within minutes when we go for IV route as in this route drug directly go to systemic circulation. Different experimental animals are utilized to check the possible outcomes of test substances that include Rabbit, mice, and rat. Various factors like dose strength, dose frequency and the meaning by which drug can be administered to animal can be examined. The emphasis on drug safety should be the main priority while injecting drug substances. Animal ethics guidelines should be followed in this regard. AEG basically provides us safety guidelines which should be followed for safety handling.

A Review of Parenteral Administration of Testing Substance in Rabbit and Mice