Open AccessFirst Report of Fatal Infection Caused by Community-acquired Methicillin-resistant Staphylococcus aureus USA300 Clone in a Collegiate Athlete
Author(s) -
Ryohei Yokomori,
Junya Tsurukiri,
Mariko Moriya,
Hiroshi Yamanaka,
Takehito Kobayashi,
Hidemasa Nakaminami,
Shunsuke Takadama,
Norihisa Noguchi,
Tetsuya Matsumoto,
Takao Arai
Publication year - 2020
Publication title -
jma journal
Language(s) - English
Resource type - Journals
eISSN - 2433-3298
pISSN - 2433-328X
DOI - 10.31662/jmaj.2019-0054
Subject(s) - staphylococcus aureus , panton–valentine leukocidin , methicillin resistant staphylococcus aureus , sepsis , leukocidin , medicine , skin infection , endocarditis , microbiology and biotechnology , biology , bacteria , genetics
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is prevalent around the world and is a causative agent of skin and soft tissue infections in healthy individuals. Particularly, Panton–Valentine leukocidin (PVL)-positive CA-MRSA strains occasionally cause life-threatening infections, such as septic pulmonary emboli (SPE) and infectious endocarditis. However, severe infections caused by PVL-positive CA-MRSA strains have rarely been reported in Japan. For the first time, this study reports the case of a 20-year-old Japanese college athlete with life-threatening PVL-positive CA-MRSA USA300 clone infection, including sepsis, SPE, and skin and soft tissue infections with iliofemoral deep venous thrombosis.