Open AccessDIAGNOSIS AND TREATMENT OF PRIMARY VAGINAL CARCINOMA IN SITU AND DYSPLASIA
Author(s) -
Punn R.,
Grönroos M.,
Meurman L.,
Liukko P.
Publication year - 1981
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348109155472
Subject(s) - medicine , carcinoma in situ , vagina , colposcopy , obstetrics and gynaecology , dysplasia , carcinoma , lesion , radiation therapy , gynecology , surgery , pregnancy , cancer , pathology , cervical cancer , biology , genetics
. Fifteen cases of primary carcinoma in situ or severe or moderate dysplasia of the vagina have been diagnosed and treated during the period 1966–75 at the Department of Obstetrics and Gynecology, Turku University Central Hospital. Because of abnormal vaginal cytology the lesion was localized by means of colposcopy and iodine staining. For 6 patients local estrogen treatment was applied to increase the thickness of the epidermal layer. For 6 patients, treatment consisted of simple excision. Nine patients, including both those with carcinoma in situ, were treated with intravaginal radiation therapy. The radiation dosage was 2000 to 2600 rad at a distance of 1 cm from the surface of the epithelium. None of the patients showed any complications, and all are now symptom‐free.