Open AccessThe cryosurgical treatment of intraepithelial neoplasia
Author(s) -
Henriksen Helen Marie
Publication year - 1979
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347909154047
Subject(s) - medicine , cryotherapy , cryosurgery , malignancy , hysterectomy , carcinoma in situ , biopsy , surgery , carcinoma , radiology , pathology
. At the Finseninstituttet and the Radium Centre in Copenhagen, from 1971‐1975 inclusive, cryosurgery was carried out altogether 59 times on 57 patients. Only 8 patients showed histopathological changes in the biopsies sufficient to indicate conization. Hysterectomy was carried out on 8 patients. In 7 of these the removed uteri showed either no malignant changes or changes of a lesser degree of malignancy than those, which had indicated cryotherapy. Invasive growth was discovered only in 1 patient, who later underwent a total hysterectomy by the Wertheim method. A biopsy on 1 patient with carcinoma in situ, suspected invasive growth, was treated with radium.