Open AccessDuration of noninvasive ventilation is not a predictor of clinical outcomes in patients with acute exacerbation of COPD and respiratory failure
Author(s) -
Laith Ghazala,
Umur Hatipoğlu,
Tanya Devnani,
Erin Covert,
Justin Hanks,
Katelyn Edwards,
Maeve G. MacMurdo,
Manshi Li,
Xiaofeng Wang,
Abhijit Duggal
Publication year - 2021
Publication title -
canadian journal of respiratory therapy
Language(s) - English
Resource type - Journals
eISSN - 2368-6820
pISSN - 1205-9838
DOI - 10.29390/cjrt-2021-021
Subject(s) - medicine , copd , mechanical ventilation , exacerbation , respiratory failure , acute exacerbation of chronic obstructive pulmonary disease , emergency department , retrospective cohort study , intensive care medicine , intensive care unit , emergency medicine , ventilation (architecture) , noninvasive ventilation , mechanical engineering , psychiatry , engineering
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity. Noninvasive ventilation (NIV) is proven to be effective in the majority of patients with acute exacerbation COPD (AECOPD) complicated with respiratory failure. NIV could be lifesaving but also can delay mechanical ventilation if its efficacy is not assessed in a timely manner. In this study, we analyzed potential predictors of NIV failure in AECOPD in a tertiary medical intensive care unit (MICU). In particular, we wondered whether duration of NIV among those who eventually failed was associated with poor outcomes.