Open Access3,5-Dicaffeoylquinic acid protects H9C2 cells against oxidative stress-induced apoptosis via activation of the PI3K/Akt signaling pathway
Author(s) -
Ye Bi,
Yuting Wu,
Ling Chen,
Zhenghuai Tan,
Huijie Fan,
Lingpeng Xie,
Wentong Zhang,
Hongmei Chen,
Jun Li,
Bin Liu,
Yingchun Zhou
Publication year - 2018
Publication title -
food and nutrition research/food and nutrition research. supplement
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 37
eISSN - 1654-6628
pISSN - 1654-661X
DOI - 10.29219/fnr.v62.1423
Subject(s) - protein kinase b , apoptosis , pi3k/akt/mtor pathway , propidium iodide , oxidative stress , ly294002 , chemistry , microbiology and biotechnology , biochemistry , biology , programmed cell death
Oxidative stress-induced apoptosis plays an important role in the development of heart failure. 3,5-Dicaffeoylquinic acid (3,5-diCQA), a phenolic compound, has shown protective effects against oxidative stress in many diseases.