Open AccessBioorganic Chemistry of Rigid-Rod Molecules: Adventures with p-Oligophenyls
Author(s) -
Yoann Baudry,
Bodo Baumeister,
Gopal Das,
David Gérard,
Stefan Matile,
Naomi Sakai,
Abhigyan Som,
Nathalie Sordé,
Pinaki Talukdar
Publication year - 2002
Publication title -
chimia international journal for chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/000942902777679948
Subject(s) - supramolecular chemistry , molecule , bioorganic chemistry , molecular recognition , chemistry , rod , nanotechnology , combinatorial chemistry , materials science , stereochemistry , biochemistry , organic chemistry , enzyme , pathology , alternative medicine , medicine
Studies on the usefulness of rigid-rod molecules to address pertinent questions of biological relevance are summarized. Emphasis is placed on (a) the supramolecular functional plasticity of p-octiphenyl ß-barrels expressed in molecular recognition (adaptable synthetic hosts), molecular translocation (adaptable synthetic ion channels) and molecular transformation (esterases, RNases), (b) molecular recognition of polarized membranes by rigid push-pull rods, as well as (c) the synthetic organic chemistry of rigid-rod molecules
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