Open AccessContrast Medium-Induced Encephalopathy after Coronary Angiography– Case Report
Author(s) -
Sebastian Andone,
Rodica Bălaşa,
Laura Bărcuțean,
Zoltán Bajkó,
Valentin Ion,
Anca Moţăţăianu,
Adina Stoian,
Smaranda Maier
Publication year - 2021
Publication title -
the journal of critical care medicine
Language(s) - English
Resource type - Journals
eISSN - 2393-1817
pISSN - 2393-1809
DOI - 10.2478/jccm-2021-0010
Subject(s) - medicine , encephalopathy , complication , contrast medium , angiography , contrast (vision) , neurology , diabetes mellitus , radiology , pathological , hypertensive encephalopathy , cerebral angiography , coronary angiography , surgery , blood pressure , myocardial infarction , endocrinology , artificial intelligence , psychiatry , computer science
Contrast-induced encephalopathy represents a rare, reversible complication that appears after intravenous or intra-arterial exposure to contrast agents. There is no consensus in the literature regarding the mechanism of action. However, the theoretical mechanism is set around the disruption of the blood-brain barrier and the contrast agents’ chemical properties. Case report The case of a 70-year-old patient, known to have hypertension and type 2 diabetes mellitus is reported. The patient had undergone a diagnostic coronary angiography during which he received 100ml of Ioversol (Optiray 350™). Soon after the procedure, the patient began experiencing a throbbing headache, followed by intense behavioural changes and aggressive tendencies. He was transferred to the Neurology Clinic. The neurological examination was without focal neurological signs; however, the patient was very aggressive and uncooperative. The CT scan revealed a mild hyper-density in the frontal lobes. MRI scan revealed no pathological changes. Conservative treatment with diuretics and hydration was administered, and the patient experienced a complete resolution of symptoms in 72 hours. Conclusion Contrast-induced encephalopathy is a possible secondary complication to contrast agents and a diagnostic challenge, and it should not be overlooked, especially following procedures that use contrast agents.