Open AccessOne-pot green synthesis of isoxazol-5(4H)-one derivatives by Dowex1-x8OH in water
Author(s) -
Davood Setamdideh
Publication year - 2016
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc160202050s
Subject(s) - environmentally friendly , one pot synthesis , catalysis , reaction conditions , simplicity , chemistry , combinatorial chemistry , mathematics , organic chemistry , physics , biology , ecology , quantum mechanics
4-arylmethylidene-3-methylisoxazol-5(4H)-ones and 4-arylmethyl-idene-3-phenylisoxazol-5(4H)-ones have been synthesized in the one-pot three-component synthesis in the presence of Dowex1-x8OH as catalyst in water. The products have been obtained in high yields (90-95%) and proper reaction times (1-5 hours). This method has eco-friendly profile and operational simplicity