Open AccessThe clinical heterogeneity of entirely nonenhancing CNS lymphoma: a case series
Author(s) -
Stephen Bowden,
Daniel Munger,
Jaclyn Thiessen,
S. Cody Schoettler Woll,
Seunggu J. Han,
Edward A. Neuwelt,
Ramon F. Barajas,
Prakash Ambady
Publication year - 2021
Publication title -
cns oncology
Language(s) - English
Resource type - Journals
eISSN - 2045-0915
pISSN - 2045-0907
DOI - 10.2217/cns-2020-0020
Subject(s) - medicine , lymphoma , incidence (geometry) , presentation (obstetrics) , dermatology , pathology , radiology , physics , optics
CNS lymphoma often presents with atypical imaging characteristics leading to delay in diagnosis and initiation of treatment. Among the most rarely reported of these is entirely nonenhancing CNS lymphoma, which is estimated at an incidence of about 1%. Here, we present three cases of nonenhancing CNS lymphoma in immune competent patients at both initial presentation and recurrence and in primary as well as secondary CNS lymphoma. Diffusion- and perfusion-weighted imaging was found helpful in diagnosis in some cases.