Open AccessOsseus metaplasia in chronic renal allograft rejection
Author(s) -
Aubrey Musa Makhoba,
Lorraine du Toit-Prinsloo
Publication year - 2017
Publication title -
african journal of nephrology
Language(s) - English
Resource type - Journals
eISSN - 2518-4601
pISSN - 2306-8205
DOI - 10.21804/20-1-900
Subject(s) - medicine , metaplasia , autopsy , lesion , pathophysiology , kidney , histology , pathology , fistula , surgery
The formation of heterotopic bone tissue outside the skeleton, known as osseous metaplasia, is a well-known phenomenon, but only a handful of cases describe this in renal allografts. We report the case of a 26-year-old female who was admitted to hospital for repair of an arteriovenous fistula of the right arm. Following her demise, the incidental finding of osseous metaplasia in the allograft kidney was made at autopsy. The pathophysiology, histology and possible clinical significance of the lesion are described.