Open AccessCardiac Complications Attributed to Hydroxychloroquine: A Systematic Review of the Literature Pre-COVID-19
Author(s) -
Georgi Fram,
Dee Dee Wang,
Kelly Malette,
Pedro Villablanca,
Guson Kang,
Kent Chak-Yu So,
Mir B. Basir,
Arfaat Khan,
John McKin,
Marcus Zervos,
William W. O’Neill
Publication year - 2021
Publication title -
current cardiology reviews
Language(s) - English
Resource type - Journals
eISSN - 1875-6557
pISSN - 1573-403X
DOI - 10.2174/1573403x16666201014144022
Subject(s) - medicine , hydroxychloroquine , covid-19 , betacoronavirus , intensive care medicine , medline , coronavirus infections , pneumonia , virology , outbreak , political science , law , disease , infectious disease (medical specialty)
Hydroxychloroquine has been used for rheumatological diseases for many decades and is considered a safe medication. With the COVID-19 outbreak, there has been an increase in reports associating cardiotoxicity with hydroxychloroquine. It is unclear if the cardiotoxic profile of hydroxychloroquine is previously underreported in the literature or is it a manifestation of COVID-19 and therapeutic interventions. This manuscript evaluates the incidence of cardiotoxicity associated with hydroxychloroquine prior to the onset of COVID-19.