Open AccessThe Usefulness of the Combination of D-Dimer and Soluble Fibrin Monomer Complex for Diagnosis of Venous Thromboembolism in Psychiatric Practice: A Prospective Study
Author(s) -
Masahiro Takeshima,
Hiroyasu Ishikawa,
Masaya Ogasawara,
Munehiro Komatsu,
Dai Fujiwara,
Yu Itoh,
Yuki Wada,
Yuki Omori,
Hidenobu Ohta,
Kazuo Mishima
Publication year - 2021
Publication title -
vascular health and risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.892
H-Index - 68
eISSN - 1178-2048
pISSN - 1176-6344
DOI - 10.2147/vhrm.s307689
Subject(s) - medicine , d dimer , cutoff , venous thromboembolism , receiver operating characteristic , prospective cohort study , predictive value , thrombosis , physics , quantum mechanics
D-dimer has the advantage of excluding venous thromboembolism (VTE) due to its high sensitivity but is disadvantageous for diagnosing VTE due to its low specificity. A method to increase the usefulness of D-dimer in the diagnosis of VTE is warranted. This study aimed to investigate the usefulness of the combination of D-dimer and soluble fibrin monomer complex (SFMC), which has been suggested as a new candidate marker for VTE, in VTE diagnosis.