Open Access<p>Non-vitamin K oral anticoagulant use in the elderly: a prospective real-world study – data from the REGIstry of patients on Non-vitamin K oral Anticoagulants (REGINA)</p>
Author(s) -
Mauro Monelli,
Mauro Molteni,
Giuseppina Cassetti,
Laura Bagnara,
Valeria De Grazia,
Lorenza C. Zingale,
Franca Zilli,
Maurizio Bussotti,
Paolo Totaro,
Beatrice De Maria,
Laura Adelaide Dalla Vecchia
Publication year - 2019
Publication title -
vascular health and risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.892
H-Index - 68
eISSN - 1178-2048
pISSN - 1176-6344
DOI - 10.2147/vhrm.s191208
Subject(s) - medicine , oral anticoagulant , prospective cohort study , vitamin , vitamin k , pediatrics , warfarin , atrial fibrillation
Numerous studies on thromboembolic prevention for non-valvular atrial fibrillation (NVAF) have shown either equal or better efficacy and safety of non-vitamin K oral anticoagulants (NOACs) compared to warfarin, even for patients aged ≥75 years. Data on elderly patients, in particular, octogenarians, are lacking. Paradoxically, this population is the one with the highest risk of bleeding and stroke with a worse prognosis. This study aims to describe safety and effectiveness of NOACs in an elderly comorbid population.