Open AccessIgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
Author(s) -
Masataka Taoka,
Nobuaki Ochi,
Ayaka Mimura,
Naruhiko Ichiyama,
Yasunari Nagasaki,
Nozomu Nakagawa,
Hiroyuki Nakanishi,
Hiromichi Yamane,
Yoshiyuki Oshiro,
Yasumasa Monobe,
Nagio Takigawa
Publication year - 2021
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s308771
Subject(s) - medicine , vasculitis , lung cancer , proteinuria , cancer , renal cell carcinoma , pathology , chemoradiotherapy , rapidly progressive glomerulonephritis , purpura (gastropod) , renal biopsy , squamous cell carcinoma of the lung , rituximab , biopsy , kidney , disease , lymphoma , ecology , biology
A 72-year-old man with locally advanced lung squamous cell carcinoma experienced red purpura on the lower legs and hematuria when the disease progressed during definitive chemoradiotherapy. He had renal dysfunction and proteinuria. Biopsy specimens of the skin lesion and kidney revealed immunoglobulin A vasculitis. Potential causes such as paraneoplastic syndrome and cancer treatment have been proposed. The administration of steroids rapidly improved the symptoms. The presentation of immunoglobulin A vasculitis is accompanied by malignancies. Clinicians should keep this syndrome in mind, even during curative-intent treatment.