Open AccessPolymorphism of IL-1β rs16944(T/C) Associated with Serum Levels of IL-1β and Subsequent Stimulation of Extracellular Matrix Degradation Affects Intervertebral Disk Degeneration Susceptibility
Author(s) -
Zhao Wang,
Xun Song,
Qingbo Fang,
Weige Xia,
AiPing Luo
Publication year - 2021
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s308653
Subject(s) - genotype , analysis of variance , medicine , univariate analysis , biology , logistic regression , gastroenterology , multivariate analysis , genetics , gene
To investigate the association of polymorphism of IL-1β rs16944(T/C) with intervertebral disk degeneration (IDD), explore the possible mechanism and evaluate the predictive value of IL-1β for IDD.