Open Access<p>Derivation and Validation of a Risk Prediction Model for Vancomycin-Associated Acute Kidney Injury in Chinese Population</p>
Author(s) -
Nana Xu,
Qiao Zhang,
Guolan Wu,
Duo Lv,
Yang Zheng
Publication year - 2020
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s253587
Subject(s) - medicine , cohort , vancomycin , acute kidney injury , incidence (geometry) , retrospective cohort study , nephrotoxicity , nomogram , population , staphylococcus aureus , kidney , physics , biology , bacteria , optics , genetics , environmental health
Vancomycin is the standard therapy for methicillin-resistant Staphylococcus aureus (MRSA) infection; however, nephrotoxicity happened with a high incidence of 15%~40%. Weighting the risk before receiving vancomycin treatment facilitates timely prevention of nephrotoxicity, but no standardized strategy exists for this purpose.