Open Access<p>Functional BDNF rs7124442 Variant Regulated by miR-922 is Associated with Better Short-Term Recovery of Ischemic Stroke</p>
Author(s) -
Binghui Liu,
Wei He,
Dinghua Liu
Publication year - 2019
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s225536
Subject(s) - brain derived neurotrophic factor , medicine , neurotrophic factors , endocrinology , genotype , neurotrophin , stroke (engine) , allele , population , oncology , receptor , biology , gene , genetics , mechanical engineering , environmental health , engineering
Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin, which contributes to the neuronal survival and synaptic plasticity. This study investigated the associations of BDNF polymorphisms at the 3'-untranslated region with risk and outcome of ischemic stroke in a Chinese Han population.