Open AccessClinical Management of Relapsed/Refractory Hemophagocytic Lymphohistiocytosis in Adult Patients: A Review of Current Strategies and Emerging Therapies
Author(s) -
Halil Yıldız,
Sarah Bailly,
Éric Van Den Neste,
Jean Cyr Yombi
Publication year - 2021
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s195538
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , refractory (planetary science) , alemtuzumab , hematopoietic stem cell transplantation , regimen , young adult , pediatrics , transplantation , disease , physics , astrobiology
Haemophagocytic lymphohistiocytosis (HLH) is a severe disorder with high mortality. The aim of this review is to update clinical management of relapsed/refractory HLH in adults, with a focus on current and new therapies.