Open AccessEvaluation of NLRP3 (rs10754558) and PTPN22 (1858C/T) (rs2476601) Functional Polymorphisms in Psoriasis Susceptibility in Egypt
Author(s) -
Abeer Ahmed ALrefai,
Ashraf Dawood,
Wafaa Ahmed Shehata,
Mohammed Elhelbawy,
Nesreen G Elhelbawy
Publication year - 2021
Publication title -
application of clinical genetics
Language(s) - English
Resource type - Journals
ISSN - 1178-704X
DOI - 10.2147/tacg.s319065
Subject(s) - psoriasis , medicine , ptpn22 , dermatology , genetics , biology , single nucleotide polymorphism , genotype , gene
Psoriasis is a complex autoimmune multifactorial disease induced by interaction of environmental and genetic factors. This research aimed to clarify the association of NLRP3 (rs10754558) and PTPN22 (1858C/T) (rs2476601) polymorphisms with susceptibility to psoriasis.