Open Access<p>Role of Adiponectin Gene and Receptor Polymorphisms and Their mRNA Levels with Serum Adiponectin Level in Myocardial Infarction</p>
Author(s) -
Amany A. Saleh,
Safaa I. Tayel,
Awny Gamal Shalaby,
Sherin Sobhy El Naidany
Publication year - 2020
Publication title -
application of clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.879
H-Index - 32
ISSN - 1178-704X
DOI - 10.2147/tacg.s282843
Subject(s) - adiponectin , genotype , medicine , allele , myocardial infarction , genotyping , endocrinology , adiponectin receptor 1 , biology , receptor , gene , genetics , insulin resistance , obesity
Genetic factors are vital participants in the development and progression of myocardial infarction (MI). Adiponectin has been assumed to have a protective role in MI and adiponectin receptors variants could be a determinant for atherosclerosis. We aimed to evaluate the prevalence of ADIPOQ (rs2241766) and ADIPOR2 (rs10773989) polymorphisms and their association with mRNA levels and circulatory adiponectin levels in patients with MI.