Open AccessThe Oral Health of Patients with DiGeorge Syndrome (22q11) Microdeletion: A Case Report
Author(s) -
Estephanía Candelo,
Maria Alejandra Estrada-Mesa,
Adriana Jaramillo,
Carlos Humberto Martínez-Cajas,
Julio Osorio,
Harry Pachajoa
Publication year - 2021
Publication title -
application of clinical genetics
Language(s) - English
Resource type - Journals
ISSN - 1178-704X
DOI - 10.2147/tacg.s280066
Subject(s) - medicine , microstomia , enamel hypoplasia , malocclusion , craniofacial , oral hygiene , hypoplasia , amelogenesis imperfecta , craniofacial abnormality , digeorge syndrome , anodontia , dentistry , hypodontia , periodontist , pediatrics , enamel paint , psychiatry
DiGeorge syndrome (DG) is a genetic disorder associated with 22q11 deletion. It involves various phenotypes, including craniofacial abnormalities, congenital heart disorders, endocrine dysfunction, cognitive deficits, and psychiatric disorders. Cases commonly involve multiple anomalies. However, little is known about the condition of the oral cavity in this disorder, although palate fissure, abnormal mandible, malocclusion, and tooth hypoplasia have been identified. We aimed to determine the odontological features of patients with 22q11.2 microdeletion, in relation to gingival health and oral hygiene. We report the systemic manifestations of nine patients and results of oral evaluation of two patients. In the oral examination, oral hygiene and gingivitis were evaluated.