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Among the Jordanian population, brain tumors are the tenth most common type of cancers in both males and females, comprising 2.8% of all newly diagnosed neoplasms. Diffuse gliomas are the most prevalent and the most aggressive primary brain tumors in adults. The incidence of diffuse gliomas varies among different populations; this variation is partially linked to genetic polymorphisms. The purpose of the study is to examine the association between (BRCA1 rs799917G&gt;A, rs1799966T&gt;C, EXO1 rs1047840G&gt;A, EME1 rs12450550T&gt;C, ERCC2 rs13181T&gt;G, rs1799793C&gt;T, and XRCC1 rs1799782G&gt;A) DNA repair gene polymorphisms and glioblastoma multiforme (GBM) susceptibility, and survival in the Jordanian Arab population.

the application of clinical genetics

&lt;p&gt;The Impact of the Genetic Polymorphism in DNA Repair Pathways on Increased Risk of Glioblastoma Multiforme in the Arab Jordanian Population: A Case–Control Study&lt;/p&gt;