Open Access<p>CCR2 Genetic Polymorphism And Its Potential Effect On HIV Acquisition In A Population Of Children Living In The Northern Region Of Cameroon</p>
Author(s) -
Marie Nicole Ngoufack,
Céline Nguefeu Nkenfou,
Barbara Atogho Tiedeu,
Linda Chapdeleine Mekue Mouafo,
Béatrice Dambaya,
Elvis Ndukong Ndzi,
Charles Kouanfack,
Georges NguefackTsague,
Wilfred Fon Mbacham,
Alexis Ndjolo
Publication year - 2019
Publication title -
application of clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.879
H-Index - 32
ISSN - 1178-704X
DOI - 10.2147/tacg.s202498
Subject(s) - population , polymorphism (computer science) , human immunodeficiency virus (hiv) , genetics , biology , medicine , demography , genotype , environmental health , gene , virology , sociology
The association of chemokine receptor-2 (CCR2) polymorphism with HIV transmission or disease progression remains highly controversial. The role of CCR2-64I allele in HIV infection may differ from one population to another because of their genetic background. The objectives of this study were to characterize the CCR2 genetic polymorphism and to determine its potential effect in HIV acquisition in children living in the Northern Region of Cameroon.