Open AccessCorrelation of Visceral Obesity and Interleukin-6 Level on LUTS Due to Benign Prostatic Enlargement
Author(s) -
Bambang Sasongko Noegroho,
Safendra Siregar,
Albert Ivan Simangunsong
Publication year - 2021
Publication title -
research and reports in urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.506
H-Index - 20
ISSN - 2253-2447
DOI - 10.2147/rru.s310269
Subject(s) - medicine , lower urinary tract symptoms , obesity , prostate , urology , correlation , prostate cancer , gastroenterology , endocrinology , cancer , geometry , mathematics
Benign prostatic enlargement (BPE) is a common condition in older men causing lower urinary tract symptoms (LUTS). Numerous studies have shown correlations of obesity and age as risk factors of LUTS due to BPE. However, there are only a few studies showing the increase of interleukin-6 (IL-6) as a risk factor in LUTS. IL-6 expression is regulated in the prostate. IL-6 was found to be increased in several conditions, such as infection, inflammation, and obesity. The aim of this study is to correlate visceral obesity and IL-6 expression in the prostate with BPE and LUTS.