Open AccessAtypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous prostate biopsy are significant predictors of cancer during a transperineal template-guided saturation biopsy aimed at sampling one core for each 1 mL of prostate volume
Author(s) -
Yasushi Nakai,
Nobumichi Tanaka,
Makito Miyake,
Shunta Hori,
Yoshihiro Tatsumi,
Yosuke Morizawa,
Tomomi Fujii,
Noboru Konishi,
Kiyohide Fujimoto
Publication year - 2017
Publication title -
research and reports in urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.506
H-Index - 20
ISSN - 2253-2447
DOI - 10.2147/rru.s148424
Subject(s) - medicine , biopsy , intraepithelial neoplasia , prostate cancer , high grade prostatic intraepithelial neoplasia , prostate , urology , rectal examination , prostate biopsy , radiology , prostate specific antigen , cancer , pathology
The objective of this study was to evaluate whether high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP) predict prostate cancer (PCa) during repeat transperineal template saturation biopsy with a high number of cores per prostate volume in patients with persistent clinical suspicion of PCa who underwent at least one previous negative transrectal ultrasound (TRUS)-guided biopsy.