Open AccessPerformance of Chromosomal Microarray Analysis for Detection of Copy Number Variations in Fetal Echogenic Bowel
Author(s) -
Xiangqun Fan,
Hailong Huang,
Xiyao Lin,
Huili Xue,
Meiying Cai,
Na Lin,
Liangpu Xu
Publication year - 2021
Publication title -
risk management and healthcare policy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 22
ISSN - 1179-1594
DOI - 10.2147/rmhp.s299806
Subject(s) - karyotype , copy number variation , aneuploidy , fetus , chromosome , prenatal diagnosis , chromosomal translocation , products of conception , chromosome abnormality , biology , pregnancy , medicine , obstetrics , pathology , genetics , gestation , genome , gene
Fetal echogenic bowel (FEB) is associated with an increased risk of poor pregnant outcomes; however, karyotyping fails to detect copy number variations (CNVs) in FEB. This study aimed to evaluate the performance of chromosomal microarray analysis (CMA) for detection of FEB.