Open AccessCycle Threshold Values in the Context of Multiple RT-PCR Testing for SARS-CoV-2
Author(s) -
Daniel Romero-Álvarez,
Daniel Garzon-Chavez,
Franklin Espinosa,
Edison Ligña,
Enrique Terán,
Francisco Mora,
Emilia Espín,
Cristina Albán,
Juan Miguel Galarza,
Jorge E. Fernández Reyes
Publication year - 2021
Publication title -
risk management and healthcare policy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 22
ISSN - 1179-1594
DOI - 10.2147/rmhp.s282962
Subject(s) - covid-19 , virology , context (archaeology) , pandemic , biology , computational biology , medicine , infectious disease (medical specialty) , outbreak , disease , paleontology
Discharge or follow up of confirmed coronavirus disease 2019 (COVID-19) cases depend on accurate interpretation of RT-PCR. Currently, positive/negative interpretations are based on amplification instead of quantification of cycle threshold (Ct) values, which could be used as proxies of patient infectiousness. Here, we measured Ct values in hospitalized confirmed COVID-19 patients at different times and its implications in diagnosis and follow up.