Open Access<p>Increased Risk of Clopidogrel-Induced Gastric Mucosal Erosion in Elderly Chinese Men Harboring the <em>ABCB1 3435T</em> Allele</p>
Author(s) -
Lijun Duan,
Man Li,
Fan Wang,
Yingying Cai,
Huiying Li,
Wenli Zhou,
Yuerui Li,
Qiang Chen,
Jing Bai,
Hongbin Liu
Publication year - 2020
Publication title -
risk management and healthcare policy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 22
ISSN - 1179-1594
DOI - 10.2147/rmhp.s263625
Subject(s) - clopidogrel , medicine , allele , gastroenterology , incidence (geometry) , aspirin , gene , biology , genetics , physics , optics
It is uncertain whether long-term use of clopidogrel alone can cause gastric mucosal injury. This study aimed to evaluate the relationship between ABCB1 C3435T polymorphisms, which could affect the intestinal absorption of clopidogrel, and gastric mucosal erosion in elderly Chinese men who used clopidogrel alone.