Open Access<p>Vancomycin Dosage and Its Association with Clinical Outcomes in Pediatric Patients with Gram-Positive Bacterial Infections</p>
Author(s) -
Sug Kyun Shin,
Hyun Joo Jung,
SangMin Jeon,
Young-Joon Park,
Jung-Woo Chae,
Hyo-In Yun
Publication year - 2020
Publication title -
risk management and healthcare policy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 22
ISSN - 1179-1594
DOI - 10.2147/rmhp.s244836
Subject(s) - medicine , trough concentration , vancomycin , trough (economics) , propensity score matching , cohort , retrospective cohort study , trough level , cohort study , nephrotoxicity , gram , therapeutic drug monitoring , gastroenterology , dosing , pharmacokinetics , toxicity , staphylococcus aureus , biology , transplantation , macroeconomics , tacrolimus , bacteria , economics , genetics
The aim of this study was to evaluate whether vancomycin trough concentrations at initial steady state are associated with clinical and microbiological outcomes along with vancomycin-related nephrotoxicity in pediatric patients with Gram-positive bacterial (GPB) infections.