Open Access
Monitoring and Improving Adherence to Tyrosine Kinase Inhibitors in Patients with Chronic Myeloid Leukemia: A Systematic Review
Author(s) -
Bee Kim Tan,
Ping Chong Bee,
Siew Siang Chua,
LiChia Chen
Publication year - 2021
Publication title -
patient preference and adherence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.885
H-Index - 48
ISSN - 1177-889X
DOI - 10.2147/ppa.s269355
Subject(s) - medicine , psychological intervention , myeloid leukemia , systematic review , intervention (counseling) , clinical trial , medline , health care , randomized controlled trial , cohort , dasatinib , intensive care medicine , family medicine , imatinib , psychiatry , political science , law , economics , economic growth
Suboptimal adherence to tyrosine kinase inhibitors (TKIs) is a widely recognized issue compromising the disease control and survival of patients with chronic myeloid leukemia (CML). A recently published review by Heiney et al reported inconclusive findings on the effects of a broad range of adherence enhancing interventions. The current systematic review aimed to identify studies that evaluated adherence-enhancing interventions implemented by healthcare professionals and determine their effect on CML patients' medication adherence and clinical outcomes.