Open AccessGenetic Polymorphism of Drug Metabolic Gene CYPs, VKORC1, NAT2, DPYD and CHST3 of Five Ethnic Minorities in Heilongjiang Province, Northeast China
Author(s) -
Tingting Zhang,
Qiuyan Li,
Bo Dong,
Xiao Liang,
Mansha Jia,
Jing Bai,
Jingcui Yu,
Songbin Fu
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s339854
Subject(s) - genetics , single nucleotide polymorphism , haplotype , ethnic group , genotype , allele frequency , pharmacogenomics , polymorphism (computer science) , genetic diversity , genetic variation , biology , gene , genetic variability , medicine , population , environmental health , sociology , anthropology
Genetic variability in genes encoding drug-metabolizing enzymes may contribute to the heterogeneity of drug responses in different populations. Extensive research in pharmacogenomics in major populations around the world provides us with a great deal of information about drug-related genetic polymorphisms.