Open AccessWuzhi Capsule Dosage Affects Tacrolimus Elimination in Adult Kidney Transplant Recipients, as Determined by a Population Pharmacokinetics Analysis
Author(s) -
Lizhi Chen,
Yi Yang,
Xuebin Wang,
Chenyu Wang,
Lin Wang,
Zheng Jiao,
Zhuo Wang
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s321997
Subject(s) - tacrolimus , medicine , pharmacokinetics , population , cyp3a5 , pharmacology , capsule , transplantation , kidney transplantation , biology , genotype , biochemistry , botany , environmental health , gene
In this study, we aimed to establish a tacrolimus population pharmacokinetic model and better understand the drug-drug interaction between Wuzhi capsule and tacrolimus in Chinese renal transplant recipients.