Open AccessInteractive Association Between Intronic Polymorphism (rs10506151) of the LRRK2 Gene and Type 2 Diabetes on Neurodegenerative Diseases
Author(s) -
Mei-Hsuen Huang,
YuFan Liu,
Oswald Ndi Nfor,
ShuYi Hsu,
Wei-Yong Lin,
YuanShiun Chang,
YungPo Liaw
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s316158
Subject(s) - medicine , type 2 diabetes , confidence interval , lrrk2 , logistic regression , diabetes mellitus , biobank , odds ratio , genotype , polymorphism (computer science) , disease , bioinformatics , gene , oncology , endocrinology , genetics , parkinson's disease , biology
We investigated the interactive effect of rs10506151 polymorphism of the Leucine-rich repeat kinase 2 (LRRK2) gene and type 2 diabetes (T2D) on neurodegenerative disease (ND) risk.