Open AccessIDUA Gene Variants and Response to Zoledronic Acid Treatment in Chinese Women with Postmenopausal Osteoporosis
Author(s) -
Haiqing Lin,
Jin Li,
Xu Zhang,
Ting Liu,
Xindie Zhou
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s315404
Subject(s) - medicine , zoledronic acid , genotype , bone mineral , osteoporosis , polymorphism (computer science) , allele , endocrinology , gene , genetics , biology
Alpha-L-iduronidase (IDUA) rs3755955 and rs6831280 polymorphisms have been demonstrated to be associated with bone mineral density (BMD). However, no study has investigated the association of these two polymorphisms with osteoporosis (OP) susceptibility in Chinese postmenopausal women.