Open AccessIdentification and Validation of Immune-Related lncRNA Signature as a Prognostic Model for Skin Cutaneous Melanoma
Author(s) -
Ping Shuai,
Siyuan Wang,
Jinbing He,
Jianghai Chen
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s310299
Subject(s) - medicine , melanoma , receiver operating characteristic , oncology , skin cancer , immune system , survival analysis , gene , cancer , cancer research , immunology , biology , genetics
Skin cutaneous melanoma (SKCM) is the most aggressive skin cancer that results in high morbidity and mortality rate worldwide. Immune-related long non-coding RNAs (IRlncRs) play an important role in regulating gene expression in tumors. Therefore, in this study, we aimed to identify IRlncRs signature that could predict prognosis and therapeutic targets for melanoma irrespective of the gene expression levels.