Open AccessGenetic Variants, Circulating Level of MCP1 with Risk of Chronic Obstructive Pulmonary Disease: A Case-Control Study
Author(s) -
Lin Chen,
Zhimin Wang,
Lu Shen,
Yi Gao,
Meichan Li,
Defu Li
Publication year - 2021
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s303799
Subject(s) - medicine , copd , pathogenesis , population , quartile , inflammation , disease , immunology , allele , case control study , confidence interval , gene , genetics , environmental health , biology
Chronic obstructive pulmonary disease (COPD) ranks one of the major causes of mortality worldwide. Inflammation is greatly involved in the pathogenesis of COPD. Monocyte chemoattractant protein-1 (MCP1) has been implicated to play an important role in the inflammatory response of various pathological processes.