Open Access<p>Association Between Cannabinoid Receptor-1 Gene Polymorphism and the Risk of Diabetic Nephropathy Among Patients with Type 2 Diabetes Mellitus</p>
Author(s) -
Xuelian Zhang,
Haiqing Zhu,
Xiaoyan Xing,
Chunyu Zhang
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s278897
Subject(s) - medicine , odds ratio , type 2 diabetes mellitus , diabetic nephropathy , gastroenterology , genotype , body mass index , diabetes mellitus , allele , confidence interval , type 2 diabetes , genotyping , genetic model , gene polymorphism , endocrinology , genetics , gene , biology
The cannabinoid receptor 1 (CNR1) gene polymorphism is reportedly associated with components of metabolic syndrome and coronary artery diseases in patients with type 2 diabetes mellitus (T2DM). We investigated whether the common variant rs10493353 polymorphism is associated with diabetic nephropathy (DN) in T2DM patients.