Open Access<p>A Seven-NF-κB-Related Gene Signature May Distinguish Patients with Ulcerative Colitis-Associated Colorectal Carcinoma</p>
Author(s) -
Chaoyi Ge,
Liyuan Wei,
Yu Tian,
Huahong Wang
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s274258
Subject(s) - medicine , ulcerative colitis , gene signature , receiver operating characteristic , colorectal cancer , junb , oncology , cancer , gene expression , gene , biology , disease , genetics
Ulcerative colitis (UC) patients have an increased risk of colorectal cancer (CRC), and compared with sporadic CRC, ulcerative colitis-associated colorectal cancer (CAC) is more aggressive with a worse prognosis. This study aimed to identify a gene signature to predict the risk of CAC for patients with UC in remission.