Open Access<p>Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula on Alzheimer’s Disease: Coupling Network Pharmacology with GEO Database</p>
Author(s) -
Tingting Zhang,
Linlin Pan,
Yu Cao,
Nanyang Liu,
Wei Wei,
Hao Li
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s269726
Subject(s) - kegg , drugbank , systems pharmacology , adme , computational biology , akt1 , gene , signal transduction , biological pathway , medicine , bioinformatics , biology , pi3k/akt/mtor pathway , pharmacology , genetics , gene expression , gene ontology , pharmacokinetics , drug
Yizhiqingxin formula (YZQX) is a promising formula for the treatment of Alzheimer's disease (AD) with significant clinical effects. Here, we coupled a network pharmacology approach with the Gene Expression Omnibus (GEO) database to illustrate comprehensive mechanisms and screen for molecular targets of YZQX for AD treatment.