Open Access<p><em>P2RX7</em> Gene rs1718125 Polymorphism is Related with Postoperative Pain and Fentanyl Intake in Esophageal Cancer Patients</p>
Author(s) -
Charles Zheng,
Jiayu Wang,
Shengrong Xie
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s252798
Subject(s) - fentanyl , medicine , genotype , genotyping , esophageal cancer , perioperative , anesthesia , cancer pain , gastroenterology , single nucleotide polymorphism , polymorphism (computer science) , cancer , gene , biochemistry , chemistry
Prevention and control of postoperative pains are essential, which affects the prognosis and life quality of patients. Fentanyl is a widely used opioid drug for pre-, intra- and postoperative analgesia. Identifying a patient's genotype before surgery may help to control the fentanyl dose in the perioperative period.