Open Access<p>Altered Gene Expression in Acne Vulgaris Patients Treated by Oral Isotretinoin: A Preliminary Study</p>
Author(s) -
Yuchen Jiang,
Haiyan Chen,
Le Han,
Xiaoqing Xie,
Yue Zheng,
Lai Wei
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s250969
Subject(s) - acne , medicine , isotretinoin , gene , gene expression , gastroenterology , dermatology , biology , genetics
The role of gene expression changes in acne patients treated by oral isotretinoin (ISO) and in influencing the ISO therapeutic effects is still unclear. In this study, we investigated the gene profiles of patients with severe acne who responded variously to ISO therapy.