Open Access<p>Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility</p>
Author(s) -
Bingqi Wang,
Min Wang,
Xianping Li,
Min Yang,
Lei Liu
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s248548
Subject(s) - wnt signaling pathway , medicine , cervical cancer , haplotype , genotype , oncology , sanger sequencing , logistic regression , allele , genetics , gene , locus (genetics) , cancer , bioinformatics , mutation , biology
Cervical cancer is the fourth most common and fatal tumor among women worldwide. The Wnt/β-catenin signaling pathway was etiologically involved in the cervical cancer model. Herein, we aimed to investigate whether germline genetic variations within the Wnt/β-catenin pathway can be genetic risk factors of cervical cancer.